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Benfits of fasting

Benefits of Fasting for Overall Health.

Benefits of Fasting:

Fasting carries enormous health benefits. It can work wonders for human health. Nearly all the body organs and systems are benefited from it. Fasting is a powerful weight-loss tool. It improves brain functions, creates new proteins, accelerates ketone body formation. Slow aging, repair tissue, reduces inflammation, improves liver and heart functions, reduces insulin resistance. Reduce symptoms of multiple sclerosis, reduce LDL level, help in the repair of tissue, and increase Human Growth Hormone level.


“Fasting and its effects on human health” subjected to enormous research during recent years. The comforts, luxury, and ease of modern lifestyle turned us into couch potatoes. As the proverb goes,” everything comes at a price”, so our lifestyle, which has cost us our very precious commodity, our health. Modern humans are fighting with obesity, diabetes, metabolic diseases, and other countless ailments that were unheard of in the past. The human body never designed to be fed with calories rich diet three times a day. With snacks in between and with little or no physical activity.

In Detail:

Misuse and carelessness towards our natural tendencies and devastating effects on our overall health. As result hypertension, obesity, diabetes, elevated triglycerides, muscle lethargy and a slew of other diseases attack us at a very early age and we have to live with regular medication intake and speedy aging. Ramadan Fasting a gift from Allah, that overhauls, maintain, and repairs our body tissue. To negate a few of the negatives effects of a sedentary lifestyle.

Benefits of Fasting:

Ramadan Fasting immensely beneficial for our overall health. Here we explain some benefits of fasting.

  • Fasting prompts weight loss. How? Liver stores glucose as a preferential form of energy before turning to burn body fats. Research shows that it takes nearly 10 hours to deplete liver stores of energy and turning to the use of body fat.
  • People who fast regularly may experience less brain damage in case of stroke. As they are better capable to resist oxygen and energy deprivation.
  • Fasting carries robust-disease-modifying benefits esp in case of chronic diseases like obesity. Diabetes, cancer, bowel diseases, and neurodegenerative brain diseases.
  • It found that fasting improves health indicators and can slow or even reverse aging and disease processes.
  • Human studies of fasting found that independent of weight loss. improvement in disease indicators such as insulin resistance. Blood fat abnormality, hypertension, and inflammation are seen.
  • The patient of multiple sclerosis experience marked a reduction in symptoms just after two months of regular fasting.
  • More about the benefits of fasting:
  • Fasting can prompt recovery from injuries.
  • During fasting, a new protein is formed. Cells obtain protein from nonessential sources, break them down into amino acids, and these amino acids used to build new proteins. Then After Iftar, a lot of new proteins formed in the brain and elsewhere.
  • During fasting, fats used for energy, giving rise to the production of ketones. These ketones are known to influence many molecules and proteins involved in various health functions and aging.
  • A very wonderful benefit of fasting its effect on the Human Growth Hormone. HGH can skyrocket during fasting ( some research claims as much as 5 fold increase is observed).

In short, there are a lot of Benefits of Fasting and a very powerful mechanism. That reduces inflammation, protects from heart disease, reduces LDL, slows down aging. Prevents cancer, and promotes the growth of new nerve cells in the brain.

Fasting unparalleled and it has no alternative. So

Keep Fasting, Stay Healthy.

healthy liver and fatty liver

Fasting and Liver, A Miracle

Fasting in the month of Ramadan is the religious obligation for Muslims. People all over the Muslim World observe fasting for religious reasons. Only a handful of us aware of the immense physical, psychological, and somatic benefits of fasting during Ramadan. Fasting affects all our organs and organ systems in a plethora of positive ways but the human liver can get exceptional and multiple benefits from it.

We must prostrate in gratitude to Almighty Lord for such a privileged Islamic ritual. Fasting is indeed a miracle for our liver. Science is still in a very early stage of understanding the positive impacts of fasting on the human liver. The preliminary research’ results are both astonishing and eye-openers at the same time. Liver and fasting, what a great combination, let’s have a look upon the benefits of fasting.

Liver and Fasting in Ramadan:

Fasting is known to be beneficial for the health and longevity of humans. It was thought that the positive effects may be due to caloric restriction but lo and behold the total caloric restriction is nothing to do with Ramadan Fasting. During Ramadan, the overall caloric intake remains the same and is comparable to pre and post-Ramadan. With even consistent calorie intake the benefits of Ramadan’s fasting still arise in unbelievable ways.

Ramadan’s Fasting likely triggers the same cellular maintenance mechanism. As play a role in the metabolic response to caloric restriction when practiced without fasting. During fasting, nearly everything in metabolic response affected. A fairly complex process, that’s why even after decades science still struggling to find answers to some pressing questions.

Although food intake does not differ much on fasting and non-fasting days. still, a very marked decrease in body mass, cholesterol, and triglycerides was seen in Fasting humans. Fasting increases insulin sensitivity and glucose tolerance. A decrease in lipogenesis and an increase in Beta oxidation in Fasting Muslims results in a reduction of liver steatosis and inflammation.

In new experimentation researchers identified how fasting affected proteins in the liver. showing unexpected impact on fatty acid metabolism and the surprising role played by a master regulator protein. That controls many biological pathways in the liver and other organs. In particular, the researchers found that the HNF4α protein, which regulates a large number of liver genes. Plays a previously unknown role during intermittent fasting.

Here an excerpt from original research:

“For the first time, we showed that HNF4α inhibited during intermittent fasting. This downstream consequences, such as lowering the abundance of blood proteins in inflammation or affecting bile synthesis. This helps explain some of the previously known facts about intermittent fasting. The researchers also found that fasting where no food consumed all day. changed the metabolism of fatty acids in the liver.  the knowledge that applied to improvements in glucose tolerance, and the regulation of diabetes. Link:

Dr. Faisal Dar (Pakistan Kidney and Liver Institute, Lahore)

Call us at: 0341–0543883, 042-111 117 554

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Ramadan Fasting & Liver Transplant Recepients and Donors

Ramadan Fasting & Liver Transplant Recepients and Donors.

Ramadan Fasting:

Ramadan is the most sacred month of the Islamic calendar that brings immense Ajar for fasting Muslims. Every Muslim is required to fast from dawn till dusk for 29 or 30 days during the month of Ramadan. Patients, minors, pregnant and nursing mothers, and psychologically unstable are exempted from fasting. Studies showed no significant ill effect of fasting upon liver transplant recipients. In fact, biochemistry and liver enzymes appear to at the same level pre and post-Ramadan. Only serum bilirubin observed to slightly elevated during fasting but that too returns to normal after a carbohydrate-rich meal. The decision of whether to fast or not dependent upon individual patient’s underlying health condition and consideration of transplant physicians.


Muslims all over the world follow strict abstinence from any fluid, food intake, and any sexual activity. Fasting observed from dawn till dusk for 29 or 30 days. Ramadan Fardh and carries an immense reward. but patients, minors, pregnant and nursing mothers and psychologically unstable are exempted from fasting. if their physician advises them not to do so. The same rules for travelers if they choose not to fast then they allowed.

No doubt Ramdan carries immense religious, psychological, and physical benefits. But if there strong evidence that fasting during Ramadan may deteriorate the patient’s condition. Increase illness, or can cause any sort of harm, then not fasting only permissible but also the best practice according to sharia. Islam does not allow any self-harm.

During Ramadan Fasting thoroughly researched and widely debated for kidney transplant recipients but unfortunately for liver transplant recipients. the data still not very widely available. There a few recent research studies particularity aiming at liver transplant patients (most notably recent research of Qatar University) but none of them can provide strong enough foundation to arrive at any final conclusion. These research studies termed preliminary at the most. 

Here discuss how fasting during Ramadan affects liver transplant recipients and living donors.

Liver Transplant Recipients and Ramadan Fasting: 

Before considering fasting for liver transplant recipients few things must be kept in mind. First and foremost, liver transplant outcome highly specific and one model never fit for all. Second liver transplant recipients may have other underlying conditions that affect their overall health and the decision to observe fasting during Ramadan. Third, every liver transplant patient should individually monitored. and if he/she wish to fast. the decision was taken by their transplant physician.

There a lack of comprehensive data regarding the effects of intermittent fasting in liver transplant recipients. Recently research studies emerging that show fasting no significant impact on the overall health of liver transplant recipients.

According to recent research;
  • In stable allograft patients without any underlying disease fasting does not cause any negatives effects.
  • Liver enzymes, biochemistry, and all other factors have been found to almost identical pre and post fasting.
  • As the total calorie intake remain uniform before during and after Ramadan, no significant weight loss observed. BMIs reported decreasing so patients with fatty liver disease may actually benefit from fasting.
  • Patients of liver cirrhosis advised avoiding fasting.
  • Serum bilirubin level might slightly increase in liver recipients but it returns to normal after Iftar with enough carbohydrates intake.
  • If liver transplant recipients wish to fast during Ramadan it advised increasing protein intake.
  • Last but not least consult your transplant surgeon before taking any decision. Whether you may fast or not dependent upon your very specific health condition and only your physician is in the position to guide you prior to making any choices. 
  • Immunosuppressive medication dosage needs not adjusted during Ramadan. Patients have actually shown better drug compliance during Ramadan.

Ramadan Fasting for Living-donors:

Healthy liver donors do not need to take extra precautions during Ramadan. The liver size has grown back to normal size then it perfectly ok to observe fasting during Ramadan. donor wants to donate liver in the coming months after Ramadan then not fasting might be suggested to preserve the size of the liver. 

If you need any further assistance reach to us at

Dr. Faisal Dar (Pakistan Kidney and Liver Institute, Lahore)

Call us at: 0341–0543883, 042-111 117 554

Email us at


Liver transplant

Liver transplant, The Only Hope for Those With Little Hope of Life

Liver transplant:

Liver transplant is the only treatment option available for end-stage liver diseases. Patients of liver cancer, cirrhosis, fibrosis, and acute or chronic liver failure ultimately need liver from a donor. For many, the donated liver is the only hope of a second chance at life. Liver transplantation is a relatively new, fairly complicated, and very advanced form of life-saving surgery. Currently, both deceased and living donor liver transplants are performed globally. But the problem remains the same as for all types of organ transplants, long queues of awaiting patients with very few available livers from deceased donors. There is a large gap in no of patients waiting for liver transplant and no donors. The picture is more gloomy in third world countries like Pakistan. 

Living donor liver transplant can bridge this gap rapidly, with not only better outcomes but also with the minimum waiting time. Deceased donor liver transplant had been the classic choice for liver transplant in the past. Although carrying the added benefit of using a deceased donor’s liver for two recipients simultaneously, with the undeniable drawbacks.

  • Very few deceased donor livers are available
  • Unlike kidney failure patients, that can be put on dialysis until a donated kidney is available for transplant, liver failure lack any such option. So the only option remains, is the immediate liver transplant. Deceased donor livers are hard to find with long waiting lists, so liver transplants are prioritized according to “Model for end-stage liver disease”.
  • This priority system help reduces deaths on the waiting list but also requires patients to be critically ill ( in fact on the verge of death) to be qualified for a life-saving transplant.
  • Without a suitable and timely transplant, families have to bear the tragedy of seeing their loved ones inching near death with each passing day.

Living donor liver transplant:

Living donor liver transplant is the most viable option in such a situation. Our liver has the wonderful ability to regenerate itself. Using this potential as much as 60% of a person’s healthy liver is removed and transplanted into the recipient. Both the donor and recipient’s liver will grow to their normal size and function within a few weeks (as little as 6 weeks often). As much as 70% of the healthy liver has been removed with wonderful subsequent regeneration to its full size and potential. 

Living donor liver donations carry multiple benefits, most notable among them are

  • Most donors know their recipients, often they are family members or close friends. So the decision of donation is rapid and chances of compatibility are higher.
  • Living donations eliminates the waiting time needed for the availability of the deceased’s liver, so the patient receives a life-saving transplant before his/her condition worsens. A living donor can jump the line and turn things around. 
  • A transplant from living donations go more smoothly with fewer complications.
  • This is a gift of a lifetime, a life-saving act, a sadaqa Jaria and a source of immense reward in the hereafter.
More about liver transplant:

Despite these benefits, living donor liver donations are rare, in fact only 5% of all liver transplants. In Pakistan alone, more than 2 million (some analysts claim more than 2.5 million) will ultimately need a liver transplant. Nearly 10000 Pakistanis die of liver failure every year waiting for liver donations. This is partly because the surgery can frighten people. And largely because of misconceptions/lack of knowledge surrounding living donations.

Living donor transplant a very complicated surgery and needs robust knowledge and experience. we  have the expertise that is unparalleled in the local market. We pioneered living donor liver transplant, before us the only option was to travel abroad for this type of surgery.

Living donor liver transplant does not carry any risk in itself and the matching criteria are straightforward. Anybody between the ages of 18 to 55, sufficiently healthy, not extremely obese. And with blood group matching the recipient can volunteer for donation. Studies show that long term outcomes for both donor and recipients are good or better. There is no evidence that liver donations shortens the life span or increases the chances of liver diseases of the donor in any form.

Details for liver transplant donor:

This April Let’s pledge to Clear our doubts and misconceptions about living donor liver donations, encourage our friends and families. Educate the masses about the utmost importance of liver donations. Liver transplant surgery speaks volumes, see the nearly dead patients after successful transplant, and you will not recognize them, looking like new people, color in their faces, muscle mass, enthusiastic, vigorous, energetic, and teeming with new hope of a new life. To see what happens with the miracle and generosity of living donation is unbelievable.

For any information and further assistance please contact us

Dr. Faisal Dar (Pakistan Kidney and Liver Institute, Lahore)

Call us at: 0341–0543883, 042-111 117 554


Facebook: dr.faisaldar

Organ donation in Pakistan


Organ Donation Awareness:

April is observed as “donate organ save life” month. This April, springtime garden the theme. Greenery depicts hope of new life, and insects represent helping each other as a connected society. This April, let’s promote the cause of saving lives through Organ Donation Awareness, creating awareness and educating the masses.

Organ donation the surgical removal of organs from one person and transplanting, it to replace non-functional organs of another person. Legal consent of living donor or assent of the next of kin of deceased donor.

Organ donations the only hope at a new life for people with end-stage organ failure. Shortage of donated organs worldwide but Pakistan experiencing the worst situation. Here organ donation still considered a taboo. with little to no awareness, and termed as unethical or unislamic. An estimated 50000 people die of end-stage organ failure in Pakistan, helplessly waiting for an organ transplant.


April observed as organ donation month or “Donate Life” month globally, especially in America. Various cultural and motivational seminars arranged all over the world to educate and encourage masses for the cause of organ donation. April is the month to honor those who have donated their organs to save lives.

This April the theme is “springtime” garden. The garden, the greenery depicts hope, the hope of new life. The insects depict mutual connection, empathy and positive contribution towards the cause. All aspects of garden mean interconnected, helping, and lively society.

We all have the potential to serve society, to help save and enrich life. This April we urge you to be a part of a great cause, save lives, educate yourself and society about organ donations.

Pediatric Donation Transplant week will observe April 19-25 2020. Come forward, a life-saving champion, educate yourself and create awareness in your circle of influence about “living donation”. Nurture the saplings, become the hope of a new life. Help us in promoting the cause, they waiting for you with empty helpless eyes but with hopeful hearts.

Join Dr Faisal Dar clinic, on Facebook, Instagram and other social platforms, to help create awareness, and honour donors, recipients, caregivers, transplant surgeons, health professionals, pharmacists and paramedics, who are striving day and night to save lives of those waiting for a second chance at life.

What is Organ Donation?

Organ donation is the legal permission of a person to surgically remove his/her organ and transplanted to another person. There are two types of organ donations.

  • Organ and tissue donation by a living donor is a type of donation by consent while the donor is alive. In this type, organ, part of organs and specific tissues are donated either to save the life of a patient or for research purposes. Kidney, part of the liver, part of the pancreas, part of the lungs and part of the intestines can be donated by living donor.
  • Deceased donor’s organ donation is the surgical removal of the whole organ and transplanting to another person/persons, by legal assent of the next of kin.

Currently, Spain has the highest no of donors per million, followed by Portugal, Belgium, Croatia and the United States respectively. Unfortunately, there is a large gap between the no of registered donors and those waiting for transplant on a global level. Although optimised social networks efforts and focused educational interventions have created positive views about organ donation, we are still miles behind in achieving the goal, as more and more people are registered every day in the waiting list for life-saving organ transplants.

Attitudes towards Organ Donation Awareness in Pakistan:

Pakistan lack ideal health system. Health facilities for the general public are scarce and health awareness even scarcest. Organ donation is still considered a taboo in Pakistani society. Most Pakistanis have zero knowledge of organ donations, and if they have any, its source is predominantly television. People here know about kidney transplant but liver, tissue and other organ transplants are unknown to the wide chunk of the population. Most Pakistanis are not aware of living donor transplant procedures and consider the deceased’s organ donation as mutilation/dishonor to the dead body. The outlook of Pakistanis about organ donation is gradually shifting towards positive, but the majority still consider it unethical and unislamic.

Statistics about Organ donation in Pakistan:

There is an extreme shortage of donated organs globally but Pakistan in the worst imaginable situation. No exact date available but estimated that 50000 people die each year due to end-stage organ failure in Pakistan. Nearly 15000 people die of kidney failure, 10000 with liver failure, and 6500 with heart failure. These and many more unreported lives can be saved if the organs are available for donations.

If you need further assistance and authentic information please reach us at

Dr. Faisal Dar (Pakistan Kidney and Liver Institute, Lahore)

Call us at: 0341–0543883, 042-111 117 554

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